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The Associate in Science degree prepares students who plan to major in the sciences, mathematics, and health professions to transfer to a four-year university. The degree consists of 60 semester hours of credit (SHC) of college transfer courses. Students in this program develop foundational knowledge particularly in science and math but also in writing, humanities, and social sciences. In addition, they can explore specific areas of specialization such as geology, environmental science, biology, physics, mathematics, statistics, chemistry, and astronomy.

Courses in the Associate in Science degree are approved for transfer to all UNC System universities through the Comprehensive Articulation Agreement (CAA) and most North Carolina independent colleges and universities through the Independent Comprehensive Articulation Agreement (ICAA). These agreements allow students to transfer all courses earned with a C or higher to the four-year university. Students who complete the degree with a C or higher in each class and a 2.0 or higher GPA transfer with junior status and are considered to have met all general education requirements at the transfer university.